Granulating Equipment: Types and Solutions
Table of Contents
Introduction
Granulating equipment is crucial in the pharmaceutical, food, and chemical industries. It aids in the formulation of granules, ensuring consistency, and enhancing product dissolution. Understanding the various types of granulating equipment allows firms to optimize production processes.
Types of Granulating Equipment
Wet Granulation Equipment
Wet granulation involves the use of a liquid binder, facilitating the agglomeration of powder particles. The equipment typically used includes high-shear granulators and fluid bed granulators.
- High-Shear Granulators: These involve the addition of binder in a granulation bowl, efficiently mixing materials by an impeller.
- Parameters: Bowl size typically ranges from 1L to 600L, and rotating speeds vary between 100-500 rpm.
Dry Granulation Equipment
Dry granulation does not use liquid binders, making it applicable for moisture-sensitive materials. It is primarily divided into slugging and roller compaction methods.
- Roller Compactors: Compress powder into sheets, which are granulated into desired sizes.
- Parameters: Compacting force between rollers varies from 1-10 tons.
Fluid Bed Granulators
These systems suspend particles in a fluidized state using an upward airflow, allowing for uniform coating and granulation.
- Parameters: Airflow rates range from 100 to 2000 m³/h, and operating temperatures can reach up to 80°C depending on the product.
High-Shear Mixers
High shear mixers are utilized for solid-solid mixing and accommodating the addition of granulation fluid under high shear forces, leading to rapid granulation.
- Parameters: Rotational speeds: 200 to 2000 rpm, Mixer capacity: 0.5 to 1000 kg.
GETC Company Solutions
GETC delivers innovative granulation solutions customized for various industrial needs.
- Advanced High-Shear Granulators: With optimized impeller designs to enhance efficiency.
- Precision Roller Compactors: Featuring adjustable roll gaps for fine granule consistency.
- Fluid Bed Technology: Incorporates energy-efficient blowers and precise temperature controls for optimal granulation.
References
- Parikh, D. M. (Editor). (2017). 'Handbook of Pharmaceutical Granulation Technology', CRC Press.
- Nasrat, S. (2020). 'Advanced Granulation Technologies for the Pharmaceutical Industry', Journal of Applied Pharmaceutical Science, 10(06), 125-136.
- GETC Company Official Website: https://www.getc.com
