What is an IgG/IgM rapid test?

Table of Contents

1. Introduction
2. What is an IgG/IgM Rapid Test?
3. Principles of IgG/IgM Rapid Tests
4. Procedure of the Test
5. Interpretation of Results
6. Company Solutions
7. Conclusion
8. References

Introduction

The IgG/IgM rapid test is a crucial diagnostic tool designed to detect the presence of Immunoglobulin G (IgG) and Immunoglobulin M (IgM) antibodies in the human body. This test plays a significant role in diagnosing various infections, including viral and bacterial diseases.

What is an IgG/IgM Rapid Test?

An IgG/IgM rapid test is a lateral flow immunoassay used for the qualitative detection of Immunoglobulin G and M antibodies. These antibodies are indicative of immune response and can assist in identifying recent or past infections.

Principles of IgG/IgM Rapid Tests

The test operates on the principle of antigen-antibody interaction. The test strip contains immobilized antigens specific to the pathogen of interest. Upon application of the sample, antibodies in the blood bind to these antigens, producing a visible line or signal.

The longevity of the test ranges from 15 to 20 minutes with an average sensitivity of approximately 85%-98% and specificity of 92%-99%, depending on the pathogen.

Procedure of the Test

1. Collect the blood sample from the subject.
2. Apply the sample to the designated area on the test strip.
3. Add the buffer solution to facilitate fluid migration.
4. Wait for 15-20 minutes for the results to develop.

Interpretation of Results

• IgM Positive: Indicates recent infection.
• IgG Positive: Suggests past infection or exposure.
• Both IgG and IgM Positive: Signifies ongoing immune response.
• Negative: No detectable antibodies, potential lack of exposure.

Company Solutions

Abbott Laboratories

Abbott's Panbio™ COVID-19 IgG/IgM Rapid Test Device offers a sensitivity of 94.6% and a specificity of 99.9% for COVID-19 detection.

BioMedomics

BioMedomics COVID-19 IgM-IgG Rapid Test provides results within 10-15 minutes with a sensitivity of 88.66% and a specificity of 90.63%.

Cellex

The Cellex qSARS-CoV-2 IgG/IgM Rapid Test boasts a sensitivity of 93.8% and specificity of 95.6% for SARS-CoV-2 antibodies.

Conclusion

IgG/IgM rapid tests are vital for rapid diagnosis due to their ease of use and quick results. These tests complement PCR testing, offering serological insights that aid in the comprehensive understanding of infections.

References

• World Health Organization. WHO guidelines on rapid diagnostic tests.
• Centers for Disease Control and Prevention. Serology Testing for COVID-19.
• Abbott Laboratories. Panbio™ COVID-19 IgG/IgM Rapid Test Device documentation.
• BioMedomics. COVID-19 IgM/IgG Rapid Test Fact Sheet.
• Cellex. qSARS-CoV-2 IgG/IgM Rapid Test regulatory information.